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MCOPPB trihydrochloride hydrate,>98% (HPLC)

别名:MCOPPB三盐酸盐水合物;1-1-(1-甲基环辛基)-4-哌啶基-2-(3R)-3-哌啶基-1H-苯并咪唑三盐酸盐水合物;1-1-(1-Methylcyclooctyl)-4-piperidinyl-2-(3R)-3-piperidinyl-1H-benzimidazole trihydrochloride hydrate

Empirical Formula (Hill Notation): C26H40N4 · 3 HCl · xH2O CAS号: 1028969-49-4 (free base) 分子量: 518.01 (anhydrous basis) PubChem化学物质编号: 329823741
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): PZ0159
CAS号: 1028969-49-4
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$404.85

说明

包装

5, 25 mg in glass bottle
 

生化/生理作用

MCOPPB trihydrochloride is a potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist or opioid-receptor-like-1 (ORL1) receptor agonist. MCOPPB is the most potent novel non-peptide NOP full agonist in vitro and an orally potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.
 

特点和优势

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Pfizer is a registered trademark of Pfizer, Inc.
 

属性

测定

>98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to tan

溶解性

H2O: ≥13 mg/mL

创始人

Pfizer

储存温度

room temp

SMILES string

O.Cl.Cl.Cl.CC1(CCCCCCC1)N2CCC(CC2)n3c(nc4ccccc34)C@@H5CCCNC5

InChI

1S/C26H40N4.3ClH.H2O/c1-26(15-7-3-2-4-8-16-26)29-18-13-22(14-19-29)30-24-12-6-5-11-23(24)28-25(30)21-10-9-17-27-20-21;;;;/h5-6,11-12,21-22,27H,2-4,7-10,13-20H2,1H3;3*1H;1H2

InChI key

UQBVSGBDJOJHIP-UHFFFAOYSA-N

 

安全信息

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16