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LIGHT from mouse,[HVEM-L, TNFSF14];recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture

重组小鼠LIGHT是含有183个氨基酸残基的20.1kDa蛋白。NACRES NA.32
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SRP3217
增值税发票 √ 免费送货 √ 订货电话:010-68689484
¥60,202

产品描述

General description

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant human LIGHT has a calculated mass of 19.3 kDa containing 177 amino acid residues. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.

Biochem/physiol Actions

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbR, or bind to a decoy receptor, DcR3. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.

Sequence

MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV

Physical form

Lyophilized from 20mM Tris, pH 8.5 + 100 mM Arginine.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

性质

biological source  mouse
recombinant  expressed in E. coli
assay  ≥96% (HPLC)
 ≥96% (SDS-PAGE)
form  lyophilized
mol wt  20.1 kDa
packaging  pkg of 20 μg
application(s)  cell culture | mammalian: suitable
impurities  <0.1 EU/μg endotoxin, tested
color  white to off-white
UniProt accession no.  Q9QYH9
shipped in  wet ice
storage temp.  −20°C
Gene Information  mouse ... TNFSF14(50930)


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10