白粘蛋白-1，Leukadherin-1；≥98% (HPLC)

图片 白粘蛋白-1，Leukadherin-1；≥98% (HPLC)
别名：白细胞粘附素-1；4-(5-((3-苄基-4-氧代-2-硫代噻唑烷-5-亚基)甲基)呋喃-2-基)苯甲酸；4-[5-[[4-Oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid, LA1, Leukadhedrin 1, Leukadherin 1

Empirical Formula (Hill Notation): C22H15NO4S2 CAS号: 344897-95-6 分子量: 421.49 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML0886
CAS号: 344897-95-6
MDL号: MFCD01151276
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说明

生化/生理作用

Leukadherin-1 is an agonist of complement receptor-3 (CR3) and exhibits anti-inflammatory activity. It is an allosteric agonist that activates integrin by binding to a different site from the ligand binding. Leukadherin-1 plays an important role in the margination and adhesion of neutrophils to the endothelial lining of the blood vessels.[1]
Leukadherin-1 is an agonist of integrin CD11b/CD18 that can increase the extent of CD11b/CD18-dependent cell adhesion of transfected cells and of primary human and mouse neutrophils. Also, Leukadherin-1 decreases leukocyte recruitment and reduced arterial narrowing after injury in rats.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

, yellow to orange to brown

溶解性

DMSO: 3 mg/mL, clear (warmed)

储存温度

2-8°C

InChI

1S/C22H15NO4S2/c24-20-19(29-22(28)23(20)13-14-4-2-1-3-5-14)12-17-10-11-18(27-17)15-6-8-16(9-7-15)21(25)26/h1-12H,13H2,(H,25,26)/b19-12-

InChI key

AEZGRQSLKVNPCI-UNOMPAQXSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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