ITSA-1，≥98% (HPLC), solid

图片 ITSA-1，≥98% (HPLC), solid
别名：1-(2,4-二氯苯甲酰基)-1H-苯并三唑；1-(2,4-Dichlorobenzoyl)-1H-benzotriazole, Inhibitor-1 of Trichostatin A, N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide

Empirical Formula (Hill Notation): C13H7Cl2N3O CAS号: 200626-61-5 分子量: 292.12 MDL编号: MFCD00195103 PubChem化学物质编号: 24724515
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: I4159
CAS号: 200626-61-5
MDL号: MFCD00195103
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

生化/生理作用

ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct aceytlation events (histone and tubulin). ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 rreverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. Effective range 50 μM.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

solid

溶解性

DMSO: ~28 mg/mL

储存温度

2-8°C

SMILES string

Clc1ccc(c(Cl)c1)C(=O)n2nnc3ccccc23

InChI

1S/C13H7Cl2N3O/c14-8-5-6-9(10(15)7-8)13(19)18-12-4-2-1-3-11(12)16-17-18/h1-7H

InChI key

UVNLAUGZMOPBPR-UHFFFAOYSA-N

 

安全信息

监管信息

详询北实纵横科学公司
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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