Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.
Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.
Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.
The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.
|Quality Level ||100|
|biological source ||human|
|recombinant ||expressed in E. coli|
|assay ||≥98% (SDS-PAGE and HPLC)|
|form ||lyophilized powder|
|potency ||≤1.0 ng/mL|
|mol wt ||17.6 kDa|
|packaging ||pkg of 5 μg|
|storage condition ||avoid repeated freeze/thaw cycles|
|application(s) ||cell culture | mammalian: suitable|
|impurities ||endotoxin, tested|
|UniProt accession no. ||P36888|
|storage temp. ||−20°C|
|Gene Information ||human ... FLT3(2322)|
RIDADR NONH for all modes of transport