Flt-3/Flk-2 ligand human;recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)

Recombinant Human Flt-3/Flk-2/CD135/Tyrosine-protein kinase receptor FLT3;Receptor-Type Tyrosine-Protein Kinase FLT3; FL Cytokine Receptor; Fetal Liver Kinase-2; FLK-2; Fms-Like Tyrosine Kinase 3; FLT-3; Stem Cell Tyrosine Kinase 1; STK-1; CD135; FLT3; FLK2; STK1

MDL number MFCD01093789 NACRES NA.32
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): F3422
MDL号: MFCD01093789
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General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

Physical form

Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.


Quality Level  100
biological source  human
recombinant  expressed in E. coli
assay  ≥98% (SDS-PAGE and HPLC)
form  lyophilized powder
potency  ≤1.0 ng/mL
mol wt  17.6 kDa
packaging  pkg of 5 μg
storage condition  avoid repeated freeze/thaw cycles
application(s)  cell culture | mammalian: suitable
impurities  endotoxin, tested
UniProt accession no.  P36888
storage temp.  −20°C
Gene Information  human ... FLT3(2322)


个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10