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DL-甲硫氨酸 [DL-蛋氨酸],DL-Methionine;≥99.0% (NT)

别名:(±)-2-氨基-4-(甲巯基)丁酸;DL-2-氨基-4-(甲硫基)丁酸;DL甲硫氨酸;(±)-2-Amino-4-(methylmercapto)butyric acid;DL-2-Amino-4-(methylthio)butanoic acid

线性分子式: CH3SCH2CH2CH(NH2)COOH CAS号: 59-51-8 分子量: 149.21 Beilstein: 636185 EC 号: 200-432-1 MDL编号: MFCD00063096 PubChem化学物质编号: 329759959 NACRES: NA.26
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 64340
CAS号: 59-51-8
MDL号: MFCD00063096
增值税发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √
¥830.48

说明

DL-蛋氨酸已用于研究单克隆抗体开发过程中蛋氨酸对氧化的敏感性。
蛋氨酸是一种必需的氨基酸,是转甲基化和转硫的前体。在蛋白质中,L-蛋氨酸是生物活性形式。D-蛋氨酸被体内的酶转化为L-蛋氨酸。蛋氨酸的腺苷基化导致S-腺苷-L-蛋氨酸(SAM)的形成,它作为各种物质的甲基供体。众所周知,L-蛋氨酸的代谢产物谷胱甘肽可调节免疫反应并具有抗病毒作用。

应用

DL-Methionine has been used to study the susceptibility of methionine to oxidation during the development of monoclonal antibodies.[1]
 

生化/生理作用

Methionine is an essential amino acid which acts a precursor for transmethylation and transsulfuration. In proteins, L-methionine is the biologically active form. D-methionine is converted to L-methionine by enzymes in the body.[2] The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine′s metabolic product glutathione is known to regulate immune response and has antiviral action.[3]
 
 

属性

质量水平

200

测定

≥99.0% (NT)

形式

powder or crystals

旋光性

[α]/D, c = 5 in 5 M HCl (inactive)

浓度

5% in 5 M HCl

灼烧残渣

≤0.05%

颜色

white

mp

280 °C (dec.) (lit.)

溶解性

5 M HCl: 1 g/10 mL, clear, colorless to almost colorless

适用性

corresponds for TLC

application(s)

peptide synthesis

SMILES string

CSCCC(N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChI key

FFEARJCKVFRZRR-UHFFFAOYSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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