D-葡萄糖-6-磷酸二钠盐水合物，D-Glucose 6-phosphate disodium salt hydrate [G-6-P-Na2, 6-PG, G6P]；Roche

Disodium salt

 

Substrate for glucose-6-phosphatase.

 

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway.[1] Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.[2]

 

77% glucose-6-P (enzymatic), 13% sodium, 8% water

 

Contaminants: <0.2% glucose (enzymatic)

 

C₆H₁₁O₉PNa₂

 

仅用于生命科学研究。不可用于诊断。