D-(+)-海藻糖二水合物，D-(+)-Trehalose dihydrate；from Saccharomyces cerevisiae, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

General description

Trehalose is a non-reducing disaccharide, ubiquitously present in nature. It is used as a food preservative and also to retain enzymes, vaccines, cells and many other molecules.^[1] Trehalose is present as hemolymph sugar among the invertebrates.^[3]

Application

D-(+)-Trehalose dihydrate has been used in a slow-freezing method for freezing rabbit oocytes.^[3] It has also been used in solid-surface vitrification (SSV) of in vitro-matured oocytes.^[4][5] It is suitable for use as a cryoprotectant in a variety of cell freezing media.

包装

10, 25, 100 g in poly bottle

Biochem/physiol Actions

Trehalose is essential for embryogenesis, carbon metabolism, photosynthesis and flowering in plants. It predominantly exists among the species that supports anhydrobiosis (life without water).^[1] It serves as a carbohydrate reserve in microorganisms and protects them from adverse conditions,^[2] such as heat, cold, dehydration, desiccation and oxidation.^[3] Trehalose acts as a chemical chaperone affecting protein folding. It is known to prevent amyloid generation and accummulation of β-amyloid in vitro. A similar effect of trehalose has been observed with huntingtin protein aggregation. Thus, it might serve as a protective agent in Alzheimer′s disease and Huntington′s disease.^[3]

性质

安全信息