CP802079盐酸水合物，CP-802079 hydrochloride hydrate；≥98% (HPLC)

图片 CP802079盐酸水合物，CP-802079 hydrochloride hydrate；≥98% (HPLC)
别名：（{3-(4-氯苯基)-3-[4-(噻唑-羰基)-苯氧基]-丙基}-甲基氨基)乙酸盐酸盐水合物；N-[3-（4-氯苯基）-3-[4-（2-噻唑羰基）苯氧基]丙基]-N-甲基甘氨酸盐酸盐水合物；({3-(4-Chlorophenyl)-3-[4-(thiazole-carbonyl)-phenoxy]-propyl}-methyl-amino)-acetic acid hydrochloride hydrate, N-[3-(4-Chlorophenyl)-3-[4-(2-thiazolylcarbonyl)phenoxy]propyl]-N-methyl-glycine hydrochloride hydrate

Empirical Formula (Hill Notation): C22H21ClN2O4S · xHCl · yH2O CAS号: 736175-49-8 (free base) 分子量: 444.93 (anhydrous free base basis) MDL编号: MFCD18452850 PubChem化学物质编号: 329823733 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0148
CAS号: 736175-49-8
MDL号: MFCD18452850
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说明

生化/生理作用

CP-802079 is a potent and selective glycine transporter type 1 (GlyT1) antagonist. Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, they can augment NMDAR currents and NMDAR-mediated functions. CP-802,079 significantly increases the amplitude of the NMDAR currents and LTP.
 

特点和优势

This compound is featured on the Glycine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

very light brown

溶解性

DMSO: ≥20 mg/mL

创始人

Pfizer

储存温度

2-8°C

SMILES string

O.Cl.CN(CCC(Oc1ccc(cc1)C(=O)c2nccs2)c3ccc(Cl)cc3)CC(O)=O

InChI

1S/C22H21ClN2O4S.ClH.H2O/c1-25(14-20(26)27)12-10-19(15-2-6-17(23)7-3-15)29-18-8-4-16(5-9-18)21(28)22-24-11-13-30-22;;/h2-9,11,13,19H,10,12,14H2,1H3,(H,26,27);1H;1H2

InChI key

CVQXAUBKPDYXHF-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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