CP-424174，≥98% (HPLC)

5, 25 mg in glass bottle

 

CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.

 

CP-424,174 是一种细胞因子释放抑制药物 (CRID)，可抑制 IL-1b 的翻译后加工和分泌，以响应人类单核细胞中的 LPS 和 ATP。 很有可能与 CP-456,773（称为 CRID3）类似，CP-424,174 通过阻止 ASC 寡聚化来抑制 NLRP3 和 AIM2 炎症小体。

 

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