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(E)-6-(1,3-二氢-4,6-二甲氧基-7-甲基-3-氧代-5-异苯并呋喃基)-4-甲基-4-己烯酸,(E)-6-(1,3-Dihydro-4,6-dimethoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid

一种霉酚酸类似物;CasNo:38877-93-9;MDL:MFCD22375170;分子式:C18H22O6;分子量:334.37
制造商品牌: 加拿大TRC
货号(SKU): D446365
CAS号: 38877-93-9
MDL号: MFCD22375170
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Product Description

Catalogue NumberD446365
Chemical Name(E)-6-(1,3-Dihydro-4,6-dimethoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid
SynonymsMycophenolic Acid Analogue;
CAS Number38877-93-9
Molecular FormulaC₁₈H₂₂O₆
AppearanceWhite to Off-White Solid
Melting Point112-115°C
Molecular Weight334.36
StorageRefrigerator
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly)
CategoryStandards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(E)-6-(1,3-Dihydro-4,6-dimethoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid, is the Dimethoxy analogue of Mycophenolic Acid (M831500), which is an immunosuppressant drug used to prevent rejection in organ transplantation. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
 Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesSenda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16