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CCG-1423,≥98% (HPLC)

别名:N-((1-((4-氯苯基)氨基)-1-氧代丙烷-2-基)氧基)-3,5-双(三氟甲基)苯甲酰胺;CCG 1423;N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide

CAS号 285986-88-1 经验分子式(希尔表示法) C18H13ClF6N2O3 分子量 454.75 NACRES NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): SML0987
CAS号: 285986-88-1
MDL号: MFCD01566719
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¥1,389.34

产品描述

一种特定的 RhoA 通路抑制剂和血清反应因子(SRF)的转录激活剂。

包装

5, 25 mg in glass bottle

Biochem/physiol Actions

CCG-1423 is a potent and specific inhibitor of Rho pathway signaling and activation of serum response factor (SRF) transcription. CCG-1423 inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13. Also CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

性质

Quality Level  100
assay  ≥98% (HPLC)
form  powder
color  white to beige
solubility  DMSO: 5 mg/mL, clear (warmed)
storage temp.  2-8°C


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32