Bioymifi，≥98% (HPLC)

图片 Bioymifi，≥98% (HPLC)
别名：(Z)-5-(5-[(3- [4-溴苯基] -2-亚氨基-4-氧噻唑烷-5-亚甲基)甲基]呋喃-2-基)异吲哚啉-1,3-二酮；(Z)-5-(5-[(3-[4-Bromophenyl]-2-imino-4-oxothiazolidin-5-ylidene)methyl]furan-2-yl)isoindoline-1,3-dione

Empirical Formula (Hill Notation): C22H12BrN3O4S CAS号: 1420071-30-2 分子量: 494.32 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML1031
CAS号: 1420071-30-2
MDL号: MFCD28118988
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¥1,469.00

说明

生化/生理作用

Bioymifi induces apoptosis via the Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) death receptor DR5 independent of TRAIL. Bioymifi binds selectively to the extracellular domain of DR5 with little binding affinity to DR4, promoting DR5 aggregation and activation. Bioymifi caused apoptosis and cell death in a variety of human cancer cell lines including T98G human glioblastoma cells, lung cancer cell lines H460 and H1155, the cervical cancer cell line HeLa, the osteosarcoma cell line U2OS, the pancreatic carcinoma cell line Miapaca and the colon cancer cell line HT29.
 

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

orange to dark orange red

溶解性

DMSO: 2 mg/mL, clear (warmed)

储存温度

2-8°C

InChI

1S/C22H12BrN3O4S/c23-12-2-4-13(5-3-12)26-21(29)18(31-22(26)24)10-14-6-8-17(30-14)11-1-7-15-16(9-11)20(28)25-19(15)27/h1-10,24H,(H,25,27,28)/b18-10-,24-22?

InChI key

ULBOWKXOFOTCMU-NLDKGBHCSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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