生物活性小分子, Small Molecules

别名：PF06462894；6,2-二甲基丙基-2-吡啶-2-甲氧基吡啶-6,7-二氢-9H-嘧啶并[2,1-c][1,4]恶嗪-4-酮；6(R)-(2,2-Dimethyl-propyl)-2-(pyridin-2-ylmethoxy)-6,7-dihydro-9H-pyrimido[2,1-c][1,4]oxazin-4-one

Empirical Formula (Hill Notation): C18H23N3O3 分子量: 329.39 MDL编号: MFCD28137683 PubChem化学物质编号: 329823782 NACRES: NA.77

别名：PF06465469；3-[4-氨基-1-(3R)-1-(1-氧代-2-丙烯-1-基)-3-哌啶基]-1H-吡唑并[3,4-d]嘧啶-3-基]-N-[3-甲基-4-(1-甲基乙基)苯基]苯甲酰胺；3-[4-Amino-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-[3-methyl-4-(1-methylethyl)phenyl]-benzamide

Empirical Formula (Hill Notation): C30H33N7O2 CAS号: 1407966-77-1 分子量: 523.63 NACRES: NA.77

别名：PF06649283；(4R,4aR,6R,8aS)-8a-(2,4-Difluorophenyl)-4,4a,5,6,8,8a-hexahydro-4-methyl-6-(3-methyl-5-isoxazolyl)-pyrano[3,4-d][1,3]thiazin-2-amine, (4R,4aR,6R,8aS)-8a-(2,4-Difluoro-phenyl)-4-methyl-6-(3-methyl-isoxazol-5-yl)-4,4a,5,6,8,8a-hexahydro-7-oxa-3-thia-1-aza-naphthalen-2-ylamine

Empirical Formula (Hill Notation): C18H19F2N3O2S CAS号: 1621585-17-8 分子量: 379.42 MDL编号: MFCD28580118 PubChem化学物质编号: 329823797 NACRES: NA.77

别名：PF06651385；4-(3-氯-4-三氟甲氧基)苄氧基)-N-(1,2,4-噻二唑-5-基)苯磺酰胺；4-(3-Chloro-4-(trifluoromethoxy)benzyloxy)-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide, PF 06651385

Empirical Formula (Hill Notation): C16H11ClF3N3O4S2 分子量: 465.85 NACRES: NA.77

别名：PF-06651481, Bosutinib isomer；4-[(3,5-二氯-4-甲氧基苯基)氨基]-6-甲氧基-7-[3-(4-甲基-1-哌嗪基)丙氧基]-3-喹啉甲腈；4, 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile

Empirical Formula (Hill Notation): C26H29Cl2N5O3 CAS号: 1391063-17-4 分子量: 530.45 MDL编号: MFCD22418831 PubChem化学物质编号: 329823815

别名：(4S,4aR,6R,8aS)-8a-(2,4-Difluorophenyl)-4-(fluoromethyl)-6-(3-methyl-1,2-oxazol-5-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, PF 06663195, PF06663195, (4S,4aR,6R,8aS)-8a-(2,4-Difluorophenyl)-4-(fluoromethyl)-4,4a,5,6,8,8a-hexahydro-6-(3-methyl-5-isoxazolyl)-pyrano[3,4-d][1,3]thiazin-2-amine

Empirical Formula (Hill Notation): C18H18F3N3O2S CAS号: 1621585-22-5 分子量: 397.41 MDL编号: MFCD28580119 PubChem化学物质编号: 329823798 NACRES: NA.77

别名：5,8-二氯-2-[(1,2-二氢-4,6-二甲基-2-氧代-3-吡啶基)甲基]-7-(3,5-二甲基-4-异恶唑基)-3,4-二氢-1(2H)-异喹啉酮乙酸酯；5,8-Dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1(2H)-isoquinolinone acetate

Empirical Formula (Hill Notation): C22H21Cl2N3O3 · C2H4O2 CAS号: 1616287-82-1 (free base) 分子量: 506.38 PubChem化学物质编号: 329823854

别名：PF06745013；2-{4-[6-氨基-5-(4-氯苯基)吡啶-3-基]苯氧基}-2-甲基丙酸；2-{4-[6-Amino-5-(4-chloro-phenyl)-pyridin-3-yl]-phenoxy}-2-methyl-propionic acid

Empirical Formula (Hill Notation): C21H19ClN2O3 分子量: 382.84 PubChem化学物质编号: 329823810 NACRES: NA.77

别名：2-[[(1aS,7bS)-1a,2-二氢-2,2-二甲基-6-三氟甲基苯并[b]环丙吡喃-7b(1H)-甲基]-3,4-二氢-7-(4-甲基-1H-咪唑-1-基)-2H-吡啶并[1,2-a]吡嗪-1,6-二酮；2-[[(1aS,7bS)-1a,2-Dihydro-2,2-dimethyl-6-(trifluoromethyl)benzo[b]cyclopropa[d]pyran-7b(1H)-yl]methyl]-3,4-dihydro-7-(4-methyl-1H-imidazol-1-yl)-2H-pyrido[1,2-a]pyrazine-1,6-dione

Empirical Formula (Hill Notation): C26H25F3N4O3 CAS号: 1812190-38-7 分子量: 498.50 NACRES: NA.77

别名：3-氰基-N-(3-(1-异丁酰基哌啶-4-基)-1-甲基-4-三氟甲基-1H-吡咯并[2,3-b]吡啶-5-基)苯甲酰胺；3-氰基-N-[1-甲基-3-[1-（2-甲基-1-氧代丙基）-4-哌啶基]-4-三氟甲基-1H-吡咯并[2，3-b]吡啶-5-基]苯甲酰胺；3-Cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide, 3-Cyano-N-[1-methyl-3-[1-(2-methyl-1-oxopropyl)-4-piperidinyl]-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide

Empirical Formula (Hill Notation): C26H26F3N5O2 CAS号: 1892576-58-7 分子量: 497.51 NACRES: NA.77

别名：PF06747775；N-[(3R,4R)-4-氟-1- [6-[（3-甲氧基-1-甲基-1H-吡唑-4-基）氨基] -9-甲基-9H-嘌呤-2-基 ]吡咯烷-3-基]丙烯酰胺, N-[(3R,4R)-4-氟-1- [6-[（3-甲氧基-1-甲基-1H-吡唑-4-基）氨基] -9-甲基-9H-嘌呤-2-基]-3-吡咯烷基] -2-丙烯酰胺；N-[(3R,4R)-4-Fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]-2-propenamide, N-[(3R,4R)-4-Fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]pyrrolidin-3-yl]acrylamide

Empirical Formula (Hill Notation): C18H22FN9O2 CAS号: 1776112-90-3 分子量: 415.42 PubChem化学物质编号: 329823824

别名：PF06748962；3-[(3R)-3-甲基-2-氧代-3-哌啶基]-6-(5-甲基-3-喹啉基)-2(1H)吡啶酮；3-[(3R)-3-Methyl-2-oxo-3-piperidinyl]-6-(5-methyl-3-quinolinyl)-2(1H)-pyridinone

Empirical Formula (Hill Notation): C21H21N3O2 CAS号: 1952261-87-8 分子量: 347.41 NACRES: NA.77