Begacestat，≥98% (HPLC)

别名：GSI-953；5-氯-N-3,3,3-三氟-1-羟甲基-2-三氟甲基丙基]噻吩-2-磺酰胺；5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide

Empirical Formula (Hill Notation): C9H8ClF6NO3S2 CAS号: 769169-27-9 分子量: 391.74 MDL编号: MFCD18782675 PubChem化学物质编号: 329823761 NACRES: NA.77

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: PZ0187

CAS号: 769169-27-9

MDL号: MFCD18782675

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目录价.SKU-Variant

5mg
25mg [+¥3,514.30]

¥1,743.00

数量:

说明

生化/生理作用

Begacestat (GSI-953) is a selective γ-secretase inhibitor that selectively inhibits cleavage of APP over Notch.

其他说明

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

法律信息

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

manufacturer/tradename

Pfizer^®

颜色

white to tan

溶解性

DMSO: ≥15 mg/mL

创始人

Pfizer

储存温度

2-8°C

SMILES string

OC[C@@H](NS(=O)(=O)c1ccc(Cl)s1)C(C(F)(F)F)C(F)(F)F

InChI

1S/C9H8ClF6NO3S2/c10-5-1-2-6(21-5)22(19,20)17-4(3-18)7(8(11,12)13)9(14,15)16/h1-2,4,7,17-18H,3H2/t4-/m1/s1

InChI key

PSXOKXJMVRSARX-SCSAIBSYSA-N

Gene Information

human ... APH1A(51107) , APH1B(83464) , NCSTN(23385) , PSEN1(5663) , PSEN2(5664) , PSENEN(55851)

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 20 \| 欧洲Eur. ≥ 16 \| 東京Tokyo ≥ 5 \| 香港与北京 ≥ 20