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AN2/AVex-73 hydrochloride salt,Anavex2-73 HCl;≥99%

别名:1-(2,2-二苯基四氢呋喃-3-基)-N,N-二甲基甲胺盐酸盐;1-(2,2-diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride

CAS:195615-84-0;分子式:C19H24ClNO;分子量:317.86
制造商品牌: BSZH 科学公司
货号(SKU): A06136
CAS号: 195615-84-0
MDL号: MFCD30146449
增值税发票 √ 免费送货 √ 订货电话:010-68689484
¥1,362.00

产品描述

本品可溶于DMSO(35 mg/mL)

General description

一种muscarinic/σ1配体。

Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated the scopolamine- and dizocilpine-induced learning impairments. ANAVEX2-73 (300 μg/kg) also reversed the learning deficits in mice injected with Aβ(25-35) peptide, a non-transgenic Alzheimer's disease model. The neuroprotective activity of ANAVEX2-73, its mixed cholinergic/σ(1) activity, its low active dose range and its long duration of action together reinforce its therapeutic potential in Alzheimer's disease.

Anavex2-73是毒蕈碱/σ1配体。 ANAVEX2-73(0.01-3.0 mg / kg i.p.)缓解了东pol碱和地佐西平引起的学习障碍。 ANAVEX2-73(300μg/ kg)还逆转了注射Aβ(25-35)肽(一种非转基因的阿尔茨海默氏病模型)的小鼠的学习缺陷。 ANAVEX2-73的神经保护活性,其胆碱能/σ(1)混合活性,低活性剂量范围和长作用时间共同增强了其在阿尔茨海默氏病中的治疗潜力。

性质

Iupac Name1-(2,2-diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride
Inchi Code1S/C19H23NO.ClH/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17;/h3-12,18H,13-15H2,1-2H3;1H
Inchi KeyFEQOLYDPQKHFTD-UHFFFAOYSA-N


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 99 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 22 | 香港与北京 ≥ 32