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AAV亲和层析树脂,Capto AVB

Capto AVB亲和层析树脂,设计用于纯化腺相关病毒 (AAV) 的亲和层析树脂。
货号(SKU): 17372203
增值税发票 √ 免费送货 √ 订货电话:010-68689484
€1903.47

Affinity chromatography resin designed for the purification of adeno-associated virus (AAV). Capto AVB is based on a rigid base matrix, delivering excellent pressure-flow properties to AAV production.

设计用于纯化腺相关病毒 (AAV) 的亲和层析树脂。 Capto AVB 基于刚性基体,为 AAV 生产提供出色的压力流动特性。

 

  • Efficient, industrial-scale purification of AAV of several subclasses by affinity chromatography.
  • Non-mammalian derived product to reduce regulatory concerns.
  • High selectivity and excellent scalability.

The possibility to run at higher flow rates and bed heights increases flexibility in process design and allows for an increased productivity.

 

ParameterCapto AVB, 1 L
LigandRecombinant protein (Mr 14 000) produced in Saccharomyces cerevisiae. Binds AAV of subclasses 1, 2, 3, and 5 
MatrixHighly cross-linked agarose, spherical 
Particle Size150 μm 
pH stability, operational23 to 10 
pH stability, CIP32 to 12 
Flow velocity4Min. 220 cm/h 
Storage20% ethanol at temperatures between 4°C and 8°C. 
Chemical stabilityStable in commonly used aqueous buffers used in purification of AAV. 
Binding capacity/mL chromatography resinTypically, > 1012 genome copies/mL of chromatography resin 
Pack size1 L 
  • 1Median particle size of the cumulative volume distribution.
  • 2pH range where resin can be operated without significant change in function.
  • 3pH range where resin can be subjected to cleaning-in-place (CIP) without significant change in function.
  • 4Determined at < 3 bar (44 psi, 0.3 MPa) in a 1 mL column at 20 cm bed height, measured at 20°C using process buffers with the same viscosity as water.
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16