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7,8-二羟基香豆素,7,8-Dihydroxycoumarin;≥97%, powder

别名:瑞香素;Daphnetol;Daphnetin;Ruixiangsu; Empirical Formula (Hill Notation): C9H6O4 CAS号: 486-35-1 分子量: 178.14 EC 号: 207-632-8 MDL编号: MFCD00016977 PubChem化学物质编号: 24278375 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): D5564
CAS号: 486-35-1
MDL号: MFCD00016977
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¥1,233.70

说明

7,8-二羟基香豆素是蛋白激酶的抑制剂。 它是一种存在于植物中的活性内酯,如 Daphne Korean Nakai 和百里香科 Daphne。 它用作镇痛剂、抗病毒剂和抗菌剂。 7,8-二羟基香豆素被发现通过许多信号通路诱导肿瘤细胞凋亡。 因此,据信它表现出抗肿瘤作用。 7,8-二羟基香豆素也可用于治疗肺癌。 它还已知用于治疗凝血障碍和类风湿性关节炎。 已知 7,8-二羟基香豆素可诱导神经突生长并延长神经元存活。 它有助于清除引起坏死的物质,维持水电解质平衡和能量代谢。 7,8-二羟基香豆素参与神经营养因子的产生,有助于恢复神经元功能。

生化/生理作用

7,8-Dihydroxycoumarinan is an inhibitor of protein kinases. It is an active lactone present in plants such as Daphne Korean Nakai, and Thymelaeaceae Daphne. It serves as as analgesic, antiviral and antibacterial agent. 7,8-Dihydroxycoumarinan is found to induce tumor apoptosis via a number of signalling pathways. Thus, it is believed to exhibit antitumor effects. 7,8-Dihydroxycoumarinan might also be useful in treating lung carcinoma. It is also known to be used in treating coagulation disorders and rheumatoid arthritis. 7,8-Dihydroxycoumarinan is known to induce neurite growth and lengthen neuronal survival. It helps in clearing substances inducing necrosis, maintains water-electrolytes balance and energy metabolism. 7,8-Dihydroxycoumarinan is involved in the generation of neurotrophic factor and helps in restoring neuron function.
 
 

属性

质量水平

200

生物来源

synthetic (organic)

测定

≥97%

形式

powder

溶解性

ethanol: 5 mg/mL

储存温度

room temp

SMILES string

Oc1ccc2C=CC(=O)Oc2c1O

InChI

1S/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H

InChI key

ATEFPOUAMCWAQS-UHFFFAOYSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 55 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 8 | 香港与北京 ≥ 10