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7- 苄氧羰基-4-(三氟甲基)香豆素,7-Benzyloxy-4-trifluoromethylcoumarin [7-BFC];≥99% (HPLC), solid

别名:7-BFC; Empirical Formula (Hill Notation): C17H11F3O3 分子量: 320.26 MDL编号: MFCD01564466 PubChem化学物质编号: 24891807 NACRES: NA.47
制造商品牌: Sigma-Aldrich
货号(SKU): B5057
MDL号: MFCD01564466
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¥9,691.87

说明

应用

7-Benzyloxy-4-trifluoromethylcoumarin has been used:
  • in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
  • in O-dealkylation reaction to determine the activity of CYP3A
  • to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)

生化/生理作用

Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.
 

法律信息

Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.
 
 

属性

质量水平

检测方案

≥99% (HPLC)

形式

solid

储存温度

−20°C

SMILES string

FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12

InChI

1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2

InChI key

WVKLERKKJXUPIK-UHFFFAOYSA-N

Gene Information

rat ... Maoa(29253) , Maob(25750)

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 60 | 欧洲Eur. ≥ 21 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 10