6-羟基氯唑沙宗，6-Hydroxychlorzoxazone；≥98% (HPLC)

图片 6-羟基氯唑沙宗，6-Hydroxychlorzoxazone；≥98% (HPLC)
别名：5-氯-6-羟基苯并[d]恶唑-2(3H)-酮；5-氯-6-羟基-2(3H)-苯并噁唑酮；5-Chloro-6-hydroxy-2(3H)-benzoxazolone, 5-Chloro-6-hydroxybenzoxazone

Empirical Formula (Hill Notation): C7H4ClNO3 CAS号: 1750-45-4 分子量: 185.56 MDL编号: MFCD00143502 PubChem化学物质编号: 24724641
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: UC148
CAS号: 1750-45-4
MDL号: MFCD00143502
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

应用

6-hydroxy Chlorzoxazone has been used: as a reference standard to monitor substrate depletion or 6-hydroxy chlorzoxazone formation by cytochrome P450 family 2 subfamily E member 1 (CYP2E1)in recombinant human enzyme screening. 6-Hydroxychlorzoxazone has been used for high-performance liquid chromatography (HPLC)-based metabolic assays of chlorzoxazone.
6-羟基氯唑沙宗已用于基于 HPLC 的氯唑沙宗代谢分析 。
氯唑沙宗的 CYP2E1 & 1A2 代谢物。
 

包装

5, 10 mg in glass bottle
无底玻璃瓶。内含物装在插入的融合锥内。
 

生化/生理作用

6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity.
 

制备说明

6-羟基氯唑沙宗可溶于甲醇。
 
 

属性

质量水平

200,

测定

≥98% (HPLC)

颜色

white to pink

溶解性

methanol: soluble

储存温度

2-8°C

SMILES string

Oc1cc2OC(=O)Nc2cc1Cl

InChI

1S/C7H4ClNO3/c8-3-1-4-6(2-5(3)10)12-7(11)9-4/h1-2,10H,(H,9,11)

InChI key

AGLXDWOTVQZHIQ-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315 - H319 - H335

靶器官

Respiratory system

个人防护装备

dust mask type N95 (US),, Eyeshields,, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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