4-马来酰亚胺基丁酸N-羟基琥珀酰亚胺酯，4-Maleimidobutyric acid N-hydroxysuccinimide ester [GMBS]；≥90% (HPLC)

图片 4-马来酰亚胺基丁酸N-羟基琥珀酰亚胺酯，4-Maleimidobutyric acid N-hydroxysuccinimide ester [GMBS]；≥90% (HPLC)
别名：N-(4-马来酰亚胺丁酰基)琥珀酰亚胺；4-马来酰亚胺基丁酸N-琥珀酰亚胺酯；N -琥珀酰亚胺基 4-马来酰亚胺基丁酸酯；N-(γ-马来酰亚胺丁酰氧基)琥珀酰亚胺；4-Maleimidobutyric acid N-succinimidyl ester, N-(γ-Maleimidobutyryloxy)succinimide, N-Succinimidyl 4-maleimidobutyrate, GMBS

Empirical Formula (Hill Notation): C12H12N2O6 CAS号: 80307-12-6 分子量: 280.23 MDL编号: MFCD00036817
制造商品牌: 默克 Merck , 西格玛 Sigma-Aldrich
货号（SKU）: 442630-M
CAS号: 80307-12-6
MDL号: MFCD00036817
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说明

一般描述

Heterobifunctional reagent useful for preparation of conjugates such as secondary antibodies and β-galactosidase for EIA procedures or for immobilizing enzymes on solid supports.
N-γ-maleimidobutyryloxysuccinimide ester (GMBS) is an aliphatic crosslinker for immunotoxins (IT).(1) It is used for the generation of conjugated Poly-γ-D-glutamic acid.
 

应用

GMBS is suitable for use:
  • as a hetero-bifunctional cross-linking reagent for the immobilization of neural adhesion molecule L1 onto silicon dioxide surface[1]
  • for the crosslinking of biochips with functionalized gold nanoparticles[2]
  • for coating salinized capillary tube prior to neutravidin treatment in biosensor sandwich immunoassay[3]

警告

Toxicity: Irritant (B)
 

重悬

Reconstitute to 10 mg/ml in tetrahydrofuran or DMSO. Add 1 ml of this stock solution dropwise, with stirring, to 10 ml of 20 mM phosphate buffer.
 

其他说明

Rusin, K.M., et al. 1992. Biosens. Bioelectron. 7, 367.
Kitagawa, T., et al. 1983. J. Biochem. 94, 1160.
 

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

检测方案

≥90% (HPLC)

质量水平

100

形式

solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze

储存温度

−20°C

InChI

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

InChI key

PVGATNRYUYNBHO-UHFFFAOYSA-N

 

安全信息

储存分类代码

11;13 - Combustible Solids;Non Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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