4-甲基-2-戊酮 [甲基异丁基甲酮]，4-Methyl-2-pentanone [MIBK]；≥99%

4-Methyl-2-pentanone (Methyl isobutyl ketone, MIBK), an aliphatic ketone, is commonly used as an organic solvent. It is generally used as an extractant in atomic absorption spectrometry.[1] Preparation of MIBK using 2-propanol as the precursor has been reported with yield as high as 25%.[2] The rate constant for the reaction between OH radical and MIBK was found to be 1.40 ± 0.07×10¹¹cm³molecule^-1s^-1.[3] The kinetics and mechanism of photochemical reaction of MIBK in n-hexane solution has been studied.[4] The microwave spectrum of MIBK has been recorded to obtain its rotational constants and centrifugal distortion constants.[5]

 

4-Methyl-2-pentanone may be used to prepare (R)-(-)-4-methyl-2-pentanol via asymmetric hydrogenation in the presence of silica-supported starch-polysulfosiloxane-platinum complex (SiO₂-ST-Si-S-Pt).[6]