5, 25 mg in glass bottle
3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a ribonucleotide reductase inhibitor and iron chelator with anti-tumor activity.
3-aminopyridine carboxaldehyde thiosemicarbazone (3-AP) has a IC50 value of 0.3μM. It exhibits anti-proliferative activity in preclinical models of cancer, such as lung cancer. It also has an ability to increase the cytotoxicity, intracellular uptake and DNA incorporation of gemcitabine in vitro.
|Quality Level ||100|
|assay ||≥98% (HPLC)|
|color ||white to light brown|
|solubility ||DMSO: 10 meq/mL, clear|
|storage temp. ||2-8°C|
|InChI key ||XMYKNCNAZKMVQN-NYYWCZLTSA-N|
RIDADR UN 2811 6.1 / PGIII