3-AP，≥98% (HPLC)

图片 3-AP，≥98% (HPLC)
别名：[(3-氨基吡啶-2-基)亚甲基氨基]硫脲；3-Aminopyridine-2-carboxaldehyde thiosemicarbazone, 3-AP, PAN-811

Empirical Formula (Hill Notation): C7H9N5S CAS号: 143621-35-6 分子量: 195.24 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: SML0568
CAS号: 143621-35-6
MDL号: MFCD00924747
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¥907.39

说明

生化/生理作用

3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a ribonucleotide reductase inhibitor and iron chelator with anti-tumor activity.
3-aminopyridine carboxaldehyde thiosemicarbazone (3-AP) has a IC50 value of 0.3μM.[1] It exhibits anti-proliferative activity in preclinical models of cancer, such as lung cancer.[2] It also has an ability to increase the cytotoxicity, intracellular uptake and DNA incorporation of gemcitabine in vitro.[2]
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to light brown

溶解性

DMSO: 10 meq/mL, clear

储存温度

2-8°C

InChI

1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+

InChI key

XMYKNCNAZKMVQN-NYYWCZLTSA-N

 

安全信息

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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