2-{2- [2-(2-巯基乙氧基)乙氧基]乙氧基}乙醇，2-{2-[2-(2-Mercaptoethoxy)ethoxy] ethoxy}ethanol [MEEE]；97%

图片 2-{2- [2-(2-巯基乙氧基)乙氧基]乙氧基}乙醇，2-{2-[2-(2-Mercaptoethoxy)ethoxy] ethoxy}ethanol [MEEE]；97%
别名：巯基四聚乙二醇；巯基-PEG4-醇；1-巯基-11-羟基-3,6,9-三氧杂十一烷；1-Mercapto-11-hydroxy-3,6,9-trioxaundecane

Empirical Formula (Hill Notation): C8H18O4S 分子量: 210.29 MDL编号: MFCD22574773 PubChem化学物质编号: 329767336
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: 767751
CAS号: 90952-27-5
MDL号: MFCD22574773
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¥2,791.99

说明

应用

2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study.[1]
  • Oligo-ehtylene glycol of peptides and small molecules (PEGylation)
  • PEG-disulfide formation
  • ultra-thin protein-resistant monolayers
  • Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption

 

属性

质量水平

100

检测方案

97%

形式

liquid

reaction suitability

reagent type: cross-linking reagent

折射率

n20/D 1.481

密度

1.098 g/mL at 25 °C

SMILES string

OCCOCCOCCOCCS

InChI

1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2

InChI key

GKKYNULPAQDGHI-UHFFFAOYSA-N

 

安全信息

象形图

CorrosionSkull and crossbones
GHS05,GHS06

警示用语：

Danger

危险声明

H301 - H314

危险分类

Acute Tox. 3 Oral - Skin Corr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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