2-甲基-4-异噻唑啉-3-酮盐酸盐，2-Methyl-4-isothiazolin-3-one hydrochloride [MIT]；≥99%

图片 2-甲基-4-异噻唑啉-3-酮盐酸盐，2-Methyl-4-isothiazolin-3-one hydrochloride [MIT]；≥99%
别名：甲基异噻唑啉酮盐酸盐；MIT；Methylisothiazolinone hydrochloride

Empirical Formula (Hill Notation): C4H5NOS · HCl CAS号: 26172-54-3 分子量: 151.61 Beilstein/REAXYS Number: 3993054 EC 号: 247-499-3 MDL编号: MFCD06804636 PubChem化学物质编号: 24897073
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: M6045
CAS号: 26172-54-3
MDL号: MFCD06804636
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说明

2-Methyl-4-isothiazolin-3-one 盐酸盐 (MIT) 是一种已知会引起接触性皮炎和过敏的皮肤致敏剂。 它在化妆品工业中被广泛用作防腐剂。 MIT 是一种神经毒素，长时间暴露于其可能导致神经元死亡和神经突生长抑制。 它也是一种有效的抗菌剂。

一般描述

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.
 

应用

Methylisothiazolinone (MIT) has been used:
  • as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
  • to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
  • as an efficient antifungal, antibacterial agent and a substitute to thimerosal

生化/生理作用

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposer may lead to neuronal death and inhibition of neurite outgrowth. It is also a potent antibacterial agent.
 
 

属性

描述

isothiazolinone biocide

测定

≥99%

作用机制

protein synthesis | interferes

抗生素抗菌谱

fungi

储存温度

2-8°C

SMILES string

Cl[H].CN1SC=CC1=O

InChI

1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H

InChI key

SJXPQSRCFCPWQQ-UHFFFAOYSA-N

 

安全信息

警示用语：

Danger

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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