2-羟基阿托伐他汀钙盐，2-Hydroxy Atorvastatin Calcium Salt

图片 2-羟基阿托伐他汀钙盐，2-Hydroxy Atorvastatin Calcium Salt
CasNo：265989-46-6；分子式:C66H68CaF2N4O12；分子量:1187.35
制造商品牌: 加拿大TRC
货号（SKU）: H828930
CAS号: 265989-46-6
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Product Description

Catalogue NumberH828930
Chemical Name2-Hydroxy Atorvastatin Calcium Salt
Synonyms(βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1)
CAS Number265989-46-6
Alternate CAS #free acid: 214217-86-4
Molecular FormulaC₆₆H₆₈CaF₂N₄O₁₂
AppearanceWhite to Yellow Solid
Melting Point>166°C (dec.)
Molecular Weight1187.35
StorageHygroscopic, Refrigerator, under inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
StabilityHygroscopic
CategoryResearch Tools; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applicationsdi(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
ReferencesKearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
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属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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