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(2-羟丙基)-β-环糊精,(2-Hydroxypropyl)-β-cyclodextrin;average Mw ~1,380

别名:羟丙基-β-环糊精,羟丙基b环糊精,(2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN,Hydroxypropyl-beta-cyclodextrin

CAS号 128446-35-5 EINECS 编号 420-920-1 PubChem Substance ID 24859909 NACRES NA.22
货号(SKU): 332593
CAS号: 128446-35-5
MDL号: MFCD00069372
增值税发票 √ 免费货运 [顺丰 联邦] √
¥650.74

产品描述

Application

2-Hydroxylpropyl-β-cyclodextrin (HP-β-CD) is a hydroxyalkyl derivative used as formulation vehicle. It increases water solubility of the drug for successful delivery of medical agents to a biological system.[1]
HP-β-CD can be used:
• To increase the solubility of ropivacaine (RVC) upon complexation, which in turn enhances the pharmacological activity of RVC.[2]
• To increase the aqueous solubility of naproxen (NAP) in presence of polyvinylpyrrolidone (PVP.[3]
• As a template in the synthesis of hollow spherical copper sulfide nanoparticle assemblies.[4]

由于 HBC 和药物形成络合物,因此在水溶液中亲脂性药物的溶解度随着羟丙基-β-环糊精 (HBC) 的浓度线性增加。该客体-主体型络合物形成于药物和 HBC 的非极性腔之间,可引起增溶溶解。溶液可冻干生成易溶的粉末。对兔和小鼠无毒。

包装

1 kg in poly drum

5, 25, 100 g in poly bottle

性质

Quality Level200
optical activity[α]26/D +139°, c = 1 in H2O
mol wtaverage Mw ~1,380
extent of labeling0.6 molar substitution
mp278 °C (dec.)
SMILES stringCC(O)COCC1OC2OC3C(COCC(C)O)OC(OC4C(COCC(C)O)OC(OC5C(COCC(C)O)OC(OC6C(COCC(C)O)OC(OC7C(COCC(C)O)OC(OC8C(COCC(C)O)OC(OC1C(OCC(C)O)C2OCC(C)O)C(OCC(C)O)C8OCC(C)O)C(OCC(C)O)C7OCC(C)O)C(OCC(C)O)C6OCC(C)O)C(OCC(C)O)C5OCC(C)O)C(OCC(C)O)C4OCC(C)O)C(OCC(C)O)C3OCC(C)O


安全信息

个人防护装备 EyeshieldsGlovestype N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 3
闪点(华氏) Not applicable
闪点(摄氏) Not applicable
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55