General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here
for more information.
2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahdrofuran, is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis.[2] It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries.[3] Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether.[4] The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide to form secondary chlorides and primary iodides respectively.[5] On long term storage, tetrahydrofuran forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation.
Application
2-甲基四氢呋喃是可用作磷脂酰丝氨酸合成的溶剂。[1]
可用作以下情况的替代溶剂：
• DMSO（二甲基亚砜）或 MTBE（甲基叔丁基醚）在裂解酶的催化下形成 C-C 键的反应。[6]
• 格氏试剂与羰基化合物的反应。[7]
• 二氯甲烷在某些两相反应中。[8]
从可再生资源的角度看 DCM 和 THF 的绿色替代品
2-甲基四氢呋喃 (2-MeTHF)：一种在有机化学中具有广泛应用的生物质衍生溶剂
包装
1, 6×1, 2, 4×2 L in Sure/Seal™
请查看 可回收容器选项.
100, 12×100 mL in Sure/Seal™
200 L in Pure-Pac™ 2
Features and Benefits
THF、DCM、DMSO 和 MTBE 的绿色替代品
Other Notes
Pure-Pac® II 容器需要用于分配溶剂的 Micromatic MacroValve 耦合器，Z560723。
法律信息
Pure-Pac 为以下机构的注册商标： Sigma-Aldrich Co. LLC
性质
| Quality Level | 100 |
| grade | anhydrous |
| assay | ≥99.0% |
| contains | 250 ppm BHT as stabilizer |
| expl. lim. | 0.34-6.3 % |
| greener alternative product characteristics | Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry. |
| impurities | <0.002% water |
| <0.005% water (100 mL pkg) |
| evapn. residue | <0.0003% |
| refractive index | n20/D 1.406 (lit.) |
| bp | 78-80 °C (lit.) |
| mp | -136 °C |
| density | 0.86 g/mL at 25 °C (lit.) |
| SMILES string | CC1CCCO1 |
| InChI | 1S/C5H10O/c1-5-3-2-4-6-5/h5H,2-4H2,1H3| InChI key | JWUJQDFVADABEY-UHFFFAOYSA-N | |
安全信息
闪点（华氏） 14.0 °F - closed cup
闪点（摄氏） -10.0 °C - closed cup
