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1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐，(Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate [PyBOP]；purum, ≥97.0% (TLC)

CAS号 128625-52-5 线性分子式 C18H28N6OP · PF6 分子量 520.39 Beilstein/REAXYS Number 3584612 MDL number MFCD00077411 PubChem Substance ID 329749882 NACRES NA.22；别名：苯并三唑-1-基氧三吡咯烷基鏻六氟磷酸；1H-苯并三唑-1-氧三吡咯啉嗡六氟磷酸

品牌: 西格玛 Sigma-Aldrich

货号（SKU）: 12805

CAS号: 128625-52-5

MDL号: MFCD00077411

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目录价.SKU-Variant

1g
5g [+HK$548.61]
25g [+HK$3,342.16]

HK$375.36

数量:

产品描述

General description

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification.^[2] It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.^[5]

Application

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) may be used in the following studies:
• As coupling reagent in the preparation strategies for peptide-oligonucleotide conjugates.^[3]
• Synthesis of structured pure triacylglycerol (TAG) regioisomers.^[2]
• As coupling reagent in the synthesis of a 3,5-pyrazolidinedione on soluble polyethylene glycol (PEG) polymer support.^[4]
• Synthesis of herceptin- nanoparticles.^[1]

BOP 偶联剂类似物，不产生致癌副产物 HMPA。

法律信息

PyBOP 为以下机构的注册商标： Merck KGaA, Darmstadt, Germany

性质

Quality Level	200
grade	purum
assay	≥97.0% (TLC)
application(s)	peptide synthesis: suitable
mp	~150 °C
	154-156 °C (dec.) (lit.)
storage temp.	2-8°C
SMILES string	F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3ccccc23)(N4CCCC4)N5CCCC5
InChI	1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1
InChI key	VIAFLMPQBHAMLI-UHFFFAOYSA-N

安全信息

符号

GHS03,GHS07,GHS09

信号词 Danger

危害声明 H271 - H302 - H317 - H410

警示性声明 P210 - P220 - P273 - P280 - P301 + P312 - P302 + P352

个人防护装备 dust mask type N95 (US), Eyeshields, Gloves

危害码 (欧洲) Xi

风险声明 (欧洲) 36/37/38

安全声明 (欧洲) 26-36

RIDADR NONH for all modes of transport

WGK德国 WGK 3

商品规格

属性名称	属性值
储存温度 Storage temp.	2-8°C冷藏
全球实时库存 Availability √	美国St. Louis ≥ 190 \| 欧洲Eur. ≥ 66 \| 東京Tokyo ≥ 82 \| 香港与北京 ≥ 55

商品标签

pybop (3)

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1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐，(Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate [PyBOP]；purum, ≥97.0% (TLC)

产品描述

General description

Application

法律信息

性质

安全信息

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