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1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐,(Benzotriazol-1-yloxy) tripyrrolidinophosphonium hexafluorophosphate [PyBOP];purum, ≥97.0% (TLC)

CAS号 128625-52-5 线性分子式 C18H28N6OP · PF6 分子量 520.39 Beilstein/REAXYS Number 3584612 MDL number MFCD00077411 PubChem Substance ID 329749882 NACRES NA.22; 别名:苯并三唑-1-基氧三吡咯烷基鏻六氟磷酸;1H-苯并三唑-1-氧三吡咯啉嗡六氟磷酸
货号(SKU): 12805
CAS号: 128625-52-5
MDL号: MFCD00077411
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HK$375.36

产品描述

General description

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification.[2] It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.[5]

Application

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) may be used in the following studies:
• As coupling reagent in the preparation strategies for peptide-oligonucleotide conjugates.[3]
• Synthesis of structured pure triacylglycerol (TAG) regioisomers.[2]
• As coupling reagent in the synthesis of a 3,5-pyrazolidinedione on soluble polyethylene glycol (PEG) polymer support.[4]
• Synthesis of herceptin- nanoparticles.[1]

BOP 偶联剂类似物,不产生致癌副产物 HMPA。

法律信息

PyBOP 为以下机构的注册商标: Merck KGaA, Darmstadt, Germany

性质

Quality Level200
gradepurum
assay≥97.0% (TLC)
application(s)peptide synthesis: suitable
mp~150 °C
154-156 °C (dec.) (lit.)
storage temp.2-8°C
SMILES stringF[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3ccccc23)(N4CCCC4)N5CCCC5
InChI1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1
InChI keyVIAFLMPQBHAMLI-UHFFFAOYSA-N


安全信息

信号词 Danger
个人防护装备 dust mask type N95 (US)EyeshieldsGloves
危害码 (欧洲) Xi
风险声明 (欧洲) 36/37/38
安全声明 (欧洲) 26-36
RIDADR NONH for all modes of transport
WGK德国 WGK 3
商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
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