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1,2-二油酰基-sn-甘油 [18:1 DG, DOG],1-2-dioleoyl-sn-glycerol, neat oil;>99% (TLC)

别名:1-2-di-(9Z-octadecenoyl)-sn-glycerol; DG(18:1(9Z)/18:1(9Z)/0:0); DOG;(9Z)-9-Octadecenoic acid 1,1′-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl] ester, (S)-1,2-二油精, (S)-甘油-1,2-二油酸酯, 1,2-二(顺式-9-油酰基)-sn-甘油, (S)-Glycerol 1,2-dioleate, 1,2-Di(cis-9-octadecenoyl)-sn-glycerol, DG(18:1(9Z)/18:1(9Z)/0:0), DG(18:1/18:1/0:0)

CAS号 24529-88-2 经验分子式(希尔表示法) C39H72O5 分子量 620.99 NACRES NA.25
制造商品牌: 西格玛 Sigma-Aldrich
货号(SKU): 800811O
CAS号: 24529-88-2
MDL号: MFCD00148866
增值税发票 √ 免费货运 [顺丰 联邦] √
¥1,159.58

产品描述

General description

Diacylglycerol/diglyceride (DAG) is a glycerolipid, that is located at the plasma membrane.[8] It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage.[9]

Application

18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay.[6] It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay.[7] It is suitable to use in lipid-protein overlay screen assay with the recombinant protein His-AtROP6.

包装

5 mL PTFE Vial with Screw Cap (800811O-10mg)

5 mL PTFE Vial with Screw Cap (800811O-200mg)

5 mL PTFE Vial with Screw Cap (800811O-25mg)

5 mL PTFE Vial with Screw Cap (800811O-500mg)

Storage and Stability

Diacylglycerols are conveniently stored in chloroform solutions in glass vials with PTFE-lined caps at -20°C. Under these conditions acyl migration is minimal. Avoid plastic when handling chloroform solutions.

Other Notes

Delivery to cells:
Dry samples of diacylglycerol in chloroform, using a stream of nitrogen. Dissolve the residue in an appropriate volume of ethanol or DMSO, then dilute to the desired aqueous medium.

Effective concentration:
Most biological responses saturate at 20 to 250 μM sn-1,2-dioctanoylglycerol. Only sn-1,2 isomers appear to be active.

Precaution: Since short chain Diacylglycerols mimic effects of the tumor-promoting phorbol diesters in a number of biological systems, extra care should be employed in their handling. Treatment of solutions, vessels and other articles with 1N NaOH before washing or discarding will destroy diacylglycerols.

性质

assay>99% (TLC)
packagingpkg of 1 × 10 mg (with screw cap (800811O-10mg))
pkg of 2 × 100 mg (with screw cap (800811O-200mg))
pkg of 5 × 100 mg (with screw cap 800811O-500mg)
pkg of 1 × 25 mg (with screw cap (800811O-25mg))
mfr. no.Avanti Polar Lipids, 800811O
shipped indry ice
storage temp.−20°C
InChI1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37,40H,3-16,21-36H2,1-2H3/b19-17+,20-18-/t37-/m0/s1
InChI keyAFSHUZFNMVJNKX-CSWDEDFYSA-N


安全信息

RIDADR NONH for all modes of transport
WGK德国 WGK 1
商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
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