1-甲基-9H-吡啶并[3,4-b]吲哚 [哈尔满碱]，1-Methyl-9H-pyrido[3,4-b]indole [Harmane]；98%

图片 1-甲基-9H-吡啶并[3,4-b]吲哚 [哈尔满碱]，1-Methyl-9H-pyrido[3,4-b]indole [Harmane]；98%
别名：阿锐碱；2-甲基-β-咔啉；2-Methyl-β-carboline, 1-Methyl-9H-pyrido[3,4-b]indole, Aribine

Empirical Formula (Hill Notation): C12H10N2 CAS号: 486-84-0 分子量: 182.22 Beilstein: 143898 EC 号: 207-642-2 MDL编号: MFCD00004957 PubChem化学物质编号: 24846602 NACRES: NA.22
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: 103276
CAS号: 486-84-0
MDL号: MFCD00004957
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

一般描述

  • Harmane is a potent tremor-producing β-carboline alkaloid and neurotoxin.
  • It is major representative of heterocyclic aromatic amines, a group of mutagenic and carcinogenic substances which are formed in meat from the precursors creatine, creatinine, amino acids and sugars during the heating at high temperatures.
  • Blood harmane concentration is elevated in essential tremor, late-life neurological disease.

应用

  • Harmane was used in trace level determination of harmane by planar chromatography coupled with (tandem) mass spectrometry.
  • It was used to study interactions of norharman and harman with DNA.
  • It may be used as matrix for analysis of cyclodextrins and for sulfated oligosaccharides in combination with DHB as co-matrix.

生化/生理作用

I1 咪唑啉结合位点激动剂。
 

制备说明

Harmane dissolves in methanol at a concentration of 50mg/ml to form a clear, colourless to yellow solution.
 
 

属性

质量水平

100

测定

98%

drug control

stupéfiant (France)

mp

235-238 °C (lit.)

溶解性

methanol: soluble 50mg/ml

SMILES string

Cc1nccc2c3ccccc3[nH]c12

InChI

1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3

InChI key

PSFDQSOCUJVVGF-UHFFFAOYSA-N

Gene Information

human ... CYP2D6(1565)
rat ... Gabra2(29706)

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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