(±)-α-硫辛酸，(±)-α-Lipoic acid；certified reference material, pharmaceutical secondary standard

图片 (±)-α-硫辛酸，(±)-α-Lipoic acid；certified reference material, pharmaceutical secondary standard
别名： (±)-1,2-二硫戊环基-3-戊酸，6,8-二巯基辛酸，DL-α-硫辛酸，DL-6,8-硫辛酸，alpha-硫辛酸，5-(1,2-二硫戊环-3-基)戊酸；Lip(S2)，(±)-1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL-α-Lipoic acid, DL-6,8-Thioctic acid

Empirical Formula (Hill Notation): C8H14O2S2 CAS号: 1077-28-7 分子量: 206.33 Beilstein: 81853 MDL编号: MFCD00005474
制造商品牌: 西格玛 Sigma-Aldrich , 色谱科 Supelco
货号（SKU）: PHR2561
CAS号: 1077-28-7
MDL号: MFCD00005474
签订合同 √ 正规发票 √ 技术支持 √ 质量保障 √ 全程可追溯 √

说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
 

生化/生理作用

维持酶复合物（例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物）活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子（尤其是 NF-κB）的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。
 

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAC6145 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

Agency

traceable to Ph. Eur. Y0000546
traceable to USP 1368201

描述

Pharmaceutical Secondary Standard; Certified Reference Material

形式

powder

CofA

current certificate can be downloaded

包装

pkg of 1 g

储存温度

2-8°C

SMILES string

OC(=O)CCCCC1CCSS1

InChI

1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)

InChI key

AGBQKNBQESQNJD-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation markEnvironment
GHS07,GHS09

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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