青霉素G钠盐，Penicillin G sodium salt；~1650 U/mg

图片 青霉素G钠盐，Penicillin G sodium salt；~1650 U/mg
别名：苄青霉素钠；苄基青霉素钠；青霉素-G钠盐；Benzylpenicillin sodium salt；二甲基-6-(2-苯乙酰氨基)7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-甲酸钠

Empirical Formula (Hill Notation): C16H17N2NaO4S CAS号: 69-57-8 分子量: 356.37 Beilstein: 3834217 EC 号: 200-710-2 MDL编号: MFCD00069666 PubChem化学物质编号: 24899068 NACRES: NA.85
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PENNA
CAS号: 69-57-8
MDL号: MFCD00069666
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¥360.00

说明

青霉素G是一种广谱抗生素。它对肺炎链球菌、A、B、C和G组链球菌、非肺炎球菌D组链球菌、绿色链球菌和非青霉素酶产生葡萄球菌有效。青霉素G的化学结构中含有β-内酰胺环。

一般描述

Penicillin G is a narrow spectrum antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G contains β-lactam ring in their chemical structure.
 

应用

Penicillin G sodium salt has been used:
  • to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility
  • in cell culture alone as well as in combination with streptomycin and other antibiotics
  • to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining

生化/生理作用

作用机制：青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联，从而抑制细胞壁合成。
抗菌谱：本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
 

注意

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.
 

其他说明

Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin
 
 

属性

形式

powder

质量水平

200

specific activity

~1650 U/mg

溶解性

H2O: 100 mg/mL

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES string

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

FCPVYOBCFFNJFS-LQDWTQKMSA-M

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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