酒石酸氧锑钾三水合物 [吐酒石]，Potassium antimonyl tartrate trihydrate；puriss., meets analytical specification of USP, 99.0-103.0%, powder

图片 酒石酸氧锑钾三水合物 [吐酒石]，Potassium antimonyl tartrate trihydrate；puriss., meets analytical specification of USP, 99.0-103.0%, powder
别名：吐酒石；酒石酸锑钾三水合物；Antimony potassium tartrate trihydrate；Tartar emetic

Empirical Formula (Hill Notation): C8H4K2O12Sb2 · 3H2O CAS号: 28300-74-5 分子量: 667.87 EC 号: 234-293-3 MDL编号: MFCD00167056 PubChem化学物质编号: 57646885 NACRES: NA.21
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: 11126
CAS号: 28300-74-5
MDL号: MFCD00167056
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说明

一般描述

Potassium antimonyl tartrate trihydrate is a trivalent antimonial compound. It has been reported to be more toxic than pentavalent antimony (Pentostam) against Leishmania species.[1][2] Its crystal structure has been investigated by the three-dimensional X-ray and white radiation neutron diffraction techniques. It crystallizes in space group C2221. Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.[3]
 

应用

Potassium antimonyl tartrate trihydrate was employed as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum[4]†
It may also be used as a standard solution to determine the metalloid concentration such as Sb(III) and Sb(V) in surface soil, using high performance liquid chromatography coupled to inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).[5]
 
 

属性

等级

puriss.

质量水平

200

检测方案

99.0-103.0%

形式

powder

质量

meets analytical specification of USP

杂质

≤0.02 mmol/g free acid
≤0.02 mmol/g free alkali

缺失

≤2.7% loss on drying, 105 °C

mp

≥300 °C (lit.)

痕量阳离子

As: ≤150 mg/kg
Pb: ≤20 mg/kg

SMILES string

O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O

InChI

1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4

InChI key

WBTCZEPSIIFINA-UHFFFAOYSA-J

 

安全信息

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
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