辣椒平，Capsazepine；≥97% (HPLC)

图片 辣椒平，Capsazepine；≥97% (HPLC)
别名：VR1拮抗剂；N-[2-(4-氯苯基)乙基]-1,3,4,5-四氢-7,8-二羟基-2H-2-苯并氮杂卓-2-硫代甲酰胺；N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide

Empirical Formula (Hill Notation): C19H21ClN2O2S CAS号: 138977-28-3 分子量: 376.90 MDL编号: MFCD00153778
制造商品牌: 默克 Merck , 西格玛 Sigma-Aldrich
货号（SKU）: 211280
CAS号: 138977-28-3
MDL号: MFCD00153778
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¥4,536.17

说明

辣椒素和树脂毒素的竞争性拮抗剂。 Capsazepine (1 µM) 阻止辣椒素 (60 nM) 刺激的 C 纤维放电。

A competitive antagonist of Capsaicin and resiniferatoxin. Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.

一般描述

A competitive antagonist of Capsaicin (Cat. No. 211274) and resiniferatoxin. Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.
A competitive antagonist of the sensory neuron excitants capsaicin (Cat. No. 211274) and resiniferatoxin (Cat. No. 553975). Capsazepine (1 µM) blocks capsaicin (60 nM) stimulated firing of C-fibers.
 

生化/生理作用

Primary Target
A competitive antagonist of Capsaicin and resiniferatoxin
Product does not compete with ATP.
Reversible: no
Cell permeable: no
 

警告

Toxicity: Standard Handling (A)
 

重悬

Unstable in solution; reconstitute just prior to use.
 

其他说明

Fox, A.J., et al. 1995. Neuroscience 67, 741.
Ellis, J.L., and Undem, B.J. 1994. J. Pharmacol. Exp. Ther. 268, 85.
Walpole, C.S.J., et al. 1994. J. Med. Chem.37, 1942.
Szallasi, A., et al. 1993. J. Pharmacol. Exp. Therap.267, 728.
 

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
 
 

属性

storage conditions

+15C to +30C

质量水平

100

测定

≥97% (HPLC)

形式

solid

储存条件

OK to freeze

颜色

off-white

溶解性

DMSO: soluble
methanol: soluble

运输

ambient

储存温度

10-30°C

InChI

1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)

InChI key

DRCMAZOSEIMCHM-UHFFFAOYSA-N

 

安全信息

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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