盐酸甲哌卡因，Mepivacaine hydrochloride；Pharmaceutical Secondary Standard; Certified Reference Material

图片 盐酸甲哌卡因，Mepivacaine hydrochloride；Pharmaceutical Secondary Standard; Certified Reference Material
别名：盐酸甲哌卡因标准品；(±)-甲哌卡因盐酸盐；(±)-Mepivacaine hydrochloride；；1-Methyl-2,6-pipecoloxylidine hydrochloride, Carbocaine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride

Empirical Formula (Hill Notation): C15H22N2O · HCl CAS号: 1722-62-9 分子量: 282.81 EC 号: 217-023-9 MDL编号: MFCD00144738 NACRES: NA.24
制造商品牌: 色谱科 Supelco , 西格玛 Sigma-Aldrich
货号（SKU）: PHR1955
CAS号: 1722-62-9
MDL号: MFCD00144738
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¥1,773.74

说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.[1]
 

应用

Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.[2][3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
 

生化/生理作用

Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.
 

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
 

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
 

附注

To see an example of a Certificate of Analysis for this material enter LRAB1955 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
 
 

属性

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 699
traceable to Ph. Eur. M0370000
traceable to USP 1387002

API family

mepivacaine

CofA

current certificate can be downloaded

application(s)

pharmaceutical

格式

neat

储存温度

2-30°C

SMILES string

CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl

InChI

1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H

InChI key

RETIMRUQNCDCQB-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

 

安全信息

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301 - H336

危险分类

Acute Tox. 3 Oral - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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