盐酸依达比星，Idarubicin hydrochloride [DMDR, IMI-30, Idamycin]；solid

图片 盐酸依达比星，Idarubicin hydrochloride [DMDR, IMI-30, Idamycin]；solid
别名：依达比星盐酸盐；(7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, 4-Demethoxydaunorubicin hydrochloride, DMDR, IMI-30, Idamycin

Empirical Formula (Hill Notation): C26H27NO9 · HCl CAS号: 57852-57-0 分子量: 533.95 EC 号: 260-990-7 MDL编号: MFCD00866457 PubChem化学物质编号: 24278488 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: I1656
CAS号: 57852-57-0
MDL号: MFCD00866457
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说明

应用

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.
 

生化/生理作用

Topoisomerase II inhibitor
 

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 
 

属性

形式

solid

质量水平

200

创始人

Johnson & Johnson

运输

wet ice

储存温度

2-8°C

SMILES string

[H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O)O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5

InChI

1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16-,17-,21+,26-/m0/s1

InChI key

XDXDZDZNSLXDNA-TZNDIEGXSA-N

Gene Information

human ... TOP2A(7153)

 

安全信息

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险声明

H300 - H351 - H360

预防措施声明

P201 - P301 + P310 + P330

危险分类

Acute Tox. 2 Oral - Carc. 2 - Repr. 1B

储存分类代码

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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