度他雄胺，Dutasteride

图片 度他雄胺，Dutasteride
别名：(5α,17β)-N-[2,5-双(三氟甲基)苯基]-3-氧代-4-氮杂杂芳-1-烯-17-羧酰胺；17β-N-[2,5-双(三氟甲基)苯基]-氨基甲酰基-4-氮杂-5α-雄烷-1-烯-3-酮；17β-N-[2,5-Bis(trifluoromethyl)phenyl]carbamoyl-4-aza-5α-androst-1-en-3-one；(5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide

Empirical Formula (Hill Notation): C27H30F6N2O2 CAS号: 164656-23-9 分子量: 528.53 MDL编号: MFCD00937869 PubChem化学物质编号: 329825728
制造商品牌: 加拿大TRC
货号（SKU）: D735000
CAS号: 164656-23-9
MDL号: MFCD00937869
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Product Description

Catalogue NumberD735000
Chemical NameDutasteride
Synonyms(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-Indeno[5,4-f]quinoline-7-carboxamide; (5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost-1-ene-17-carboxamide; Avodart; Avolve; GG 745; GI 198745; Veltride;
CAS Number164656-23-9
Molecular FormulaC₂₇H₃₀F₆N₂O₂
AppearanceWhite to Off-White Solid
Melting Point241-243°C
Molecular Weight528.53
Storage-20°C Freezer
SolubilityDMSO (Slightly), Methanol (Slightly)
CategoryStandards; Steroids;
ApplicationsDutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
ReferencesBakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),
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属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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