双水杨酸酯，Salsalate；≥98% (HPLC)

别名：2-Hydroxybenzoic acid 2-carboxyphenyl ester, salicyloxysalicylic acid, disalicylic acid, 2-(2-Hydroxybenzoyl)oxybenzoic acid, salicylsalicylic acid

Empirical Formula (Hill Notation): C14H10O5 CAS号: 552-94-3 分子量: 258.23 EC 号: 209-027-4 MDL编号: MFCD00020252 PubChem化学物质编号: 329825134 NACRES: NA.77

制造商品牌: 西格玛 Sigma-Aldrich

货号（SKU）: SML0070

CAS号: 552-94-3

MDL号: MFCD00020252

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目录规格.SKU-Variant

50mg
250mg

说明

应用

Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.

包装

50, 250 mg in glass bottle

生化/生理作用

Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

颜色

white to tan

溶解性

DMSO: ≥15 mg/mL

储存温度

room temp

SMILES string

OC(=O)c1ccccc1OC(=O)c2ccccc2O

InChI

1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)

InChI key

WVYADZUPLLSGPU-UHFFFAOYSA-N

安全信息

象形图

GHS07,GHS09

警示用语：

Warning

危险声明

H302 - H400

预防措施声明

P273 - P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1

商品规格

属性名称	属性值
储存温度 Storage temp.	常温阴凉避光
全球实时库存 Availability √	美国St. Louis ≥ 30 \| 欧洲Eur. ≥ 10 \| 東京Tokyo ≥ 9 \| 香港与北京 ≥ 30

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