刺芒柄花素，Formononetin；≥98.0% (HPLC)

图片 刺芒柄花素，Formononetin；≥98.0% (HPLC)
别名：7-羟基-3-（4-甲氧基苯基）-4-H-1-苯并吡喃-4-酮, 7-羟基-3-（4-甲氧基苯基）色酮, 7-羟基-4′-甲氧基异黄酮, 刺芒柄花素, 刺芒柄花醇, 大豆苷元-4′-甲基醚, 鹰嘴豆素B；7-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 7-Hydroxy-3-(4-methoxyphenyl)chromone, 7-Hydroxy-4′-methoxyisoflavone, Biochanin B, Daidzein 4′-methyl ether, Formonetin, Formononetol

Empirical Formula (Hill Notation): C16H12O4 CAS号: 485-72-3 分子量: 268.26 Beilstein: 237979 EC 号: 207-623-9 MDL编号: MFCD00016948 PubChem化学物质编号: 57651100 NACRES: NA.47
制造商品牌: BSZH
货号（SKU）: F15719
CAS号: 485-72-3
MDL号: MFCD00016948
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说明

一般描述

Formononetin is an O-methylated isoflavone, a phytoestrogen. It can be found in many legumes, different species of clovers primarily in Trifolium pratense L. (red clovers), and one of the main flavonoids found in Astragalus membranaceus (Huangqi).
 

应用

Formononetin has been used:
  • as a reference standard to study export of multiple metabolites from Crocus sativus stigma extracts using liquid chromatography-photodiode array-high resolution mass spectrometry (LC-PDA-HRMS)
  • as phytoestrogen-mimetic isoflavones to test its antioxidant effects in a biomimetic environment using chemiluminescence method
  • as an authentic standard to test the isoflavones content level in both wild type and transgenic Medicago truncatula plant using high-performance liquid chromatography (HPLC)
  • to test its effects as a potential Aryl hydrocarbon receptor (AhR)-agonist on the restoration of skin barrier proteins for Atopic dermatitis (AD) treatment using different keratinocyte cell lines and human skin equivalent (HSE) model

生化/生理作用

异黄酮在红三叶草中发现。可通过（至少部分通过）诱导肠粘膜中滋养体的分离，有效对抗 贾第鞭毛虫 的感染。
Formononetin elicits antioxidant, anti-inflammatory, anti-hyperlipidemic, and cardioprotective effects. It displays antidiabetic properties known to be effective against diabetic nephropathy in type 2 diabetes mellitus. Formononetin is a well-known anti-cancer and chemotherapeutic agent that is used in cancer therapy. It also displays antimicrobial, neuroprotective, and anti-hypertensive properties.
 
 

属性

测定

≥98.0% (HPLC)

形式

solid

mp

257-261 °C

SMILES string

COc1ccc(cc1)C2=COc3cc(O)ccc3C2=O

InChI

1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3

InChI key

HKQYGTCOTHHOMP-UHFFFAOYSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
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