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鼠尾草酚,Carnosol;analytical standard, ≥98.0% (HPLC)

别名:卡诺醇;苦味酸卡那霉素;Picrosalvin; Empirical Formula (Hill Notation): C20H26O4 CAS号: 5957-80-2 分子量: 330.42 MDL编号: MFCD02752467 PubChem化学物质编号: 329757507 NACRES: NA.24
货号(SKU): 49702
CAS号: 5957-80-2
MDL号: MFCD02752467
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¥8,380.74

说明

鼠尾草酚是一种存在于草本迷迭香 (Rosmarinus officinalis) 提取物中的酚类抗氧化剂。 Carnosol 在小鼠致癌模型中抑制使用 TPA 和 DMBA 等刺激物衍生的肿瘤形成。据报道,当添加到培养细胞的上清液中时,有效剂量为 1-10 μM 或 6 μg/ml。在饮食中添加迷迭香提取物 还发现按重量计 1% 的补充剂可以降低 DMBA-DNA 加合物的频率。


鼠尾草酚是一种天然存在的植物多酚或酚类二萜,存在于迷迭香中,可作为抗氧化剂、抗癌剂和抗炎剂广泛应用。

一般描述

Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.
Carnosol is a naturally occurring phyto polyphenolor phenolic diterpene, found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent.
 

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
 

生化/生理作用

一种具有抗氧化和抗癌活性的酚类二萜。
 
 

属性

质量水平

100

生物来源

Rosemarinus officinalis L. leaves

等级

analytical standard

测定

≥98.0% (HPLC)

保质期

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

格式

neat

储存温度

−20°C

SMILES string

CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O

InChI

1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1

InChI key

XUSYGBPHQBWGAD-PJSUUKDQSA-N

 

安全信息

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 55 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 8 | 香港与北京 ≥ 10
商品标签 [tags]