Flavoxate, a flavone derivative
and a tertiary-amine antimuscarinic
possess antispasmodic properties.
It is a strong smooth muscle relaxant
that selectively acts on the pelvic region
and is used in the symptomatic treatment of overactive bladder (OAB)
Post-absorption in the gastrointestinal tract, flavoxate is localized in bladder, liver, and kidney tissues.
It mediates the inhibition of phosphodiesterase (PDE) in the urinary bladder.
Use of flavoxate aids pain relief in inflammatory disorders of the urinary tract.