Flavoxate, a flavone derivative
[1] and a tertiary-amine antimuscarinic
[2] possess antispasmodic properties.
[2] It is a strong smooth muscle relaxant
[1] that selectively acts on the pelvic region
[3] and is used in the symptomatic treatment of overactive bladder (OAB)
[1] and incontinence.
[2] Post-absorption in the gastrointestinal tract, flavoxate is localized in bladder, liver, and kidney tissues.
[1] It mediates the inhibition of phosphodiesterase (PDE) in the urinary bladder.
[1] Use of flavoxate aids pain relief in inflammatory disorders of the urinary tract.
[3]