黄嘌呤，Xanthine；≥99.5% (HPLC), purified by recrystallization

图片 黄嘌呤，Xanthine；≥99.5% (HPLC), purified by recrystallization
2,6-二羟基嘌呤；2,6-Dihydroxypurine；Empirical Formula (Hill Notation): C5H4N4O2 CAS号: 69-89-6 分子量: 152.11 Beilstein: 8733 EC 号: 200-718-6 MDL编号: MFCD00078453 PubChem化学物质编号: 24902122 NACRES: NA.51
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: X0626
CAS号: 69-89-6
MDL号: MFCD00078453
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说明

黄嘌呤或其衍生物的天然来源包括动物器官、酵母、土豆、咖啡豆和茶。黄嘌呤是一种嘌呤，由嘌呤代谢途径中的几种不同前体产生：鸟嘌呤脱氨酶的鸟嘌呤脱氨和黄嘌呤氧化还原酶的次黄嘌呤转化。
黄嘌呤已被用于通过黄嘌呤-氧化酶-细胞色素c还原法测量超氧化物歧化酶的活性。它还被用作测量不同类型牛奶中黄嘌呤氧化酶活性的底物.
黄嘌呤和黄嘌呤氧化酶用于产生超氧自由基以测量超氧化物歧化酶的活性。黄嘌呤是嘌呤代谢中尿酸的前体代谢物。它已被注意到是痛风等疾病的生物标志物。

一般描述

Natural sources of xanthine or its derivatives include animal organs, yeast, potatoes, coffee beans, and tea. Xanthine is a purine that is produced from several different precursors in the purine metabolic pathway: deamination of guanine-by-guanine deaminase and conversion of hypoxanthine by xanthine oxidoreductase.
 

应用

Xanthine has been used in the measurement of the activity of superoxide dismutase by the xanthine-oxidase-cytochrome c reduction method.[1][2] It has also been used as a substrate for the measurement of xanthine oxidase activity[3] in different types of milk[4]
 

生化/生理作用

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase. Xanthine is a precursor metabolite to uric acid in purine metabolism. It has been noted as a biomarker of conditions such as gout.
 
 

属性

质量水平

400

测定

≥99.5% (HPLC)

纯化方式

recrystallization

溶解性

1 M NaOH: soluble 50 mg/mL, clear, colorless to faintly yellow

SMILES string

O=C1NC(=O)c2nc[nH]c2N1

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

InChI key

LRFVTYWOQMYALW-UHFFFAOYSA-N

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 50 | 欧洲Eur. ≥ 12 | 東京Tokyo ≥ 20 | 香港与北京 ≥ 50
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