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黄嘌呤,Xanthine;≥99%, powder [2,6-二羟基嘌呤]

2,6-Dihydroxypurine; CAS号 69-89-6 经验分子式(希尔表示法) C5H4N4O2 分子量 152.11 Beilstein/REAXYS Number 8733 EINECS 编号 200-718-6 MDL number MFCD00078453 PubChem Substance ID 24902144 NACRES NA.51
货号(SKU): X7375
CAS号: 69-89-6
MDL号: MFCD00078453
增值税发票 √ 免费货运 [顺丰 联邦] √
HK$692.25

产品描述

黄嘌呤是在鸟嘌呤脱氨酶存在下由鸟嘌呤合成的。 黄嘌呤氧化酶催化次黄嘌呤产生黄嘌呤,然后分解为尿酸。黄嘌呤衍生物存在于咖啡,茶和可可种子中。 黄嘌呤已被提出作为产生药理活性化合物的先导。黄嘌呤已被用于构巢曲霉运输测定中不可辐射的底物混合物中。 它也已被用作黄嘌呤氧化酶的底物,以在g细胞和藻类细胞中产生超氧阴离子。高水平的黄嘌呤与代谢性疾病(如Lesch-Nyhan综合征)有关。 基于黄嘌呤的生物传感器可用于检测食品和临床样品中的黄嘌呤。 肾功能衰竭,痛风和黄嘌呤尿症患者的血液和尿液样本显示高水平的黄嘌呤。

General description

Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid.[3] Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.[4]

Application

Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay.[6] It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells[7] and algal cells.[8]

包装

10, 25, 100 g in poly bottle

Biochem/physiol Actions

A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples.[3] Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine.[5]

性质

Quality Level200
biological sourcesynthetic (organic)
assay≥99%
formpowder
solubility1 M NaOH: soluble 50 mg/mL, clear to slightly hazy
NH4OH: freely soluble
NaOH: freely soluble
SMILES stringO=C1NC(=O)c2nc[nH]c2N1
InChI1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
InChI keyLRFVTYWOQMYALW-UHFFFAOYSA-N


安全信息

符号
GHS07  GHS07
信号词
Warning
危害声明 H317 - H319
警示性声明 P280 - P305 + P351 + P338
危害码 (欧洲) Xi
风险声明 (欧洲) 36-43
安全声明 (欧洲) 36/37
RIDADR NONH for all modes of transport
WGK德国 WGK 3
RTECS ZD7700000
闪点(华氏) Not applicable
闪点(摄氏) Not applicable
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 190 | 欧洲Eur. ≥ 66 | 東京Tokyo ≥ 82 | 香港与北京 ≥ 55
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