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高分辨率苯基疏水相互作用层析树脂,Capto Phenyl ImpRes hydrophobic interaction chromatography resin

Capto Phenyl ImpRes是一种HIC树脂,用于下游纯化过程中的高分辨率中间体和精制步骤。17548403;17548401;17548402;17548404
货号(SKU): 17548403
增值税发票 √ 免费送货 √ 订货电话:010-68689484
€381.39

Capto Phenyl ImpRes is a HIC resin for high-resolution intermediate and polishing steps in a downstream purification process.

将 Capto 树脂的高流动特性与较小的粒径相结合,可提供出色的压力/流动特性和分辨率。
由于流速和床高的操作窗口很大,因此工艺设计灵活。
更高的吞吐量可能会提高生产率和流程经济性。
出色的化学稳定性允许使用标准 CIP 溶液进行清洁,包括 1 M 氢氧化钠。
Resin 满足工业对供应安全性、强大性能和监管支持的需求。
令人印象深刻的分辨率和工艺设计灵活性
Capto Phenyl ImpRes 提供令人印象深刻的分辨率,同时保持出色的压力流动特性。这是通过将 Capto 树脂的高流动特性与小粒径相结合来实现的。

使用更高流速和更高床层高度的能力也增加了工艺设计的灵活性。 Capto Phenyl ImpRes 是基于高流量琼脂糖 Capto 产品线的扩展高分辨率平台的一部分。

  • Combines the high-flow characteristics of Capto resins with a smaller particle size to deliver both excellent pressure/flow properties and resolution.
  • Flexible process design due to a large operational window of flow velocities and bed heights.
  • Higher throughput might enable improved productivity and process economy.
  • Excellent chemical stability allows cleaning with standard CIP solutions, including 1 M sodium hydroxide.
  • Resin fulfills industrial demands for security of supply, robust performance, and regulatory support.

Impressive resolution and process design flexibility

Capto Phenyl ImpRes delivers impressive resolution while maintaining excellent pressure-flow properties. This is achieved by combining the high-flow characteristics of Capto resin with a small particle size.

The ability to use higher flow rates and greater bed heights also increases flexibility in process design. Capto Phenyl ImpRes is part of an expanded high-resolution platform based on the high-flow agarose Capto product line.

Prepacked columns and other formats

Capto Phenyl ImpRes resin is available in the following formats: 

Process development scale: prepacked

  • HiScreen Capto Phenyl ImpRes columns, optimized for method and process development.
  • PreDictor Capto Phenyl ImpRes RoboColumn™ units, miniaturized columns for high-throughput process development.

Lab scale: prepacked for manual purification

HiTrap Capto Phenyl ImpRes columns, for easy use with a syringe, peristaltic pump, or chromatography system.

Lab scale: prepacked for automated purification and analysis

HiTrap Capto Phenyl ImpRes columns, for easy use with a syringe, peristaltic pump, or chromatography system.

Process characterization: resin kits

Process Characterization Kit Capto Phenyl ImpRes, designed for studying the potential impact that resin ligand density might have on the process outcome.

Process-scale purification: prepacked

ReadyToProcess Capto Phenyl ImpRes columns, 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.

 

ParameterCapto Phenyl ImpRes, 1 L
Chromatography techniqueHydrophobic Interaction Chromatography 
BioProcess resinYes 
LigandPhenyl 
MatrixHigh Flow Agarose 
Particle Size36-44 μm (d50V
Binding Capacity/ml Chromatography Medium19 mg BSA/mL resin 
Ligand densityApproximately 9 μmol/mL medium 
pH stability, operational12–13 
pH stability, CIP22–14 
Pressure/Flow Specification300 kPa at min. 220 cm/h, 1 m diameter column, 20 cm bed height 
Storage20% Ethanol at 4°C to 30°C 
Chemical stability1 M NaOH, commonly used aqueous buffers 
Pack size1 L 
  • 1pH range where resin can be operated without significant change in function.
  • 2pH range where resin can be subjected to cleaning- or sanitization-in-place without significant change in function.
商品规格
属性名称属性值
储存温度 Storage temp.常温阴凉避光
全球实时库存 Availability √美国St. Louis ≥ 33 | 欧洲Eur. ≥ 27 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 16