<br /> Empirical Formula (Hill Notation): C17H20O6 CAS号: 24280-93-1 分子量: 320.34 Beilstein: 1295848 EC 号: 246-119-3 MDL编号: MFCD00036814 PubChem化学物质编号: 24896854 NACRES: NA.76">
霉酚酸(MPA)由紧凑型短青霉产生,是肌苷一磷酸脱氢酶的选择性抑制剂,从而抑制T和B淋巴细胞的DNA合成。它还被证明是一种免疫抑制剂,并且是人类淋巴和单核细胞系中单核细胞分化和凋亡的诱导剂。作为选择剂,MPA用于表达E。黄嘌呤鸟嘌呤磷酸核糖基转移酶的大肠杆菌基因,建议使用25μg/mL。
Penicillium brevicompactum
300
BioReagent
powder
cell culture | mammalian: suitable
white to yellow-white
<143.0 °C
methanol: 50 mg/mL
enzyme | inhibits
2-8°C
COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(O)=O
1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
HPNSFSBZBAHARI-RUDMXATFSA-N
human ... IMPDH1(3614) , IMPDH2(3615)
Danger
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Repr. 1B - STOT RE 1 Oral
Immune system
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK 3
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges