降烟碱-D4，(R,S)-Nornicotine-d4

图片 降烟碱-D4，(R,S)-Nornicotine-d4
别名：氘代降烟碱；(±)-Nornicotine-d4；CasNo：66148-18-3；分子式:C9H8D4N2；分子量:152.23
制造商品牌: 加拿大TRC
货号（SKU）: N757010
CAS号: 66148-18-3
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Product Description

Catalogue NumberN757010
Chemical Name(R,S)-Nornicotine-d4
Synonyms3-(2-Pyrrolidinyl)pyridine-d4; (±)-1'-Demethylnicotine-d4; (±)-3-(2-Pyrrolidinyl)pyridine-d4; (±)-1'-Demethylnicotine-d4; (±)-Nornicotine-d4; 2-(3-Pyridinyl)pyrrolidine-d4; 3-(Pyrrolidin-2-yl)pyridine-d4;
CAS Number66148-18-3
Alternate CAS #5746-86-1-unlabelled
Molecular FormulaC₉H₈D₄N₂
AppearanceColourless to Pale Yellow Oil
Molecular Weight152.23
StorageAmber Vial, -20°C Freezer, Under inert atmosphere
SolubilityChloroform (Slightly), Methanol (Slightly)
StabilityLight Sensitive
CategoryStandards; Isotopic Labeled Analogues; Stimulant; Nicotine Derivatives and Metabolites;
ApplicationsLabelled (RS)-Nornicotine (N757000). (RS)-Nornicotine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity.
ReferencesHecht, S., et al.: Carcinogenesis, 9, 875 (1988), Rivenson, A., et al.: Cancer Res., 48, 6912 (1988), Hoffmann, D., et al.: Chem. Res. Toxicol., 14, 767 (2001), Kool, J., et al.: J. Med. Chem., 49, 3287 (2006), Kool, J., et al.: Drug Metab. Dispos., 35, 640 (2007),
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属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 30 | 欧洲Eur. ≥ 10 | 東京Tokyo ≥ 9 | 香港与北京 ≥ 30
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