阿非迪霉素，Aphidicolin from Nigrospora sphaerica；≥98% (HPLC), powder

图片 阿非迪霉素，Aphidicolin from Nigrospora sphaerica；≥98% (HPLC), powder
别名：艾菲地可宁；黑孢菌蚜虫素；阿非科林；Empirical Formula (Hill Notation): C20H34O4 CAS号: 38966-21-1 分子量: 338.48 Beilstein: 4689958 MDL编号: MFCD00083214 PubChem化学物质编号: 57653817 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: A0781
CAS号: 38966-21-1
MDL号: MFCD00083214
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说明

蚜虫素是一种抗生素，一种有效的抗病毒和抗有丝分裂剂以及DNA聚合酶抑制剂。

生化/生理作用

Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
 

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
 

注意

Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.
 
 

属性

质量水平

300

测定

≥98% (HPLC)

形式

powder

旋光性

[α]27/D +12°, c = 1 in methanol(lit.)

颜色

white

mp

227-233 °C (lit.)

溶解性

ethanol: 1 mg/mL (stable at least a week at 4°C.)
DMSO: 10 mg/mL (stable at least six weeks at −20°C.)
methanol: 10 mg/mL
H2O: insoluble

抗生素抗菌谱

neoplastics
viruses

作用机制

DNA synthesis | interferes

储存温度

2-8°C

SMILES string

[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4

InChI

1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1

InChI key

NOFOAYPPHIUXJR-APNQCZIXSA-N

Gene Information

human ... POLA1(5422) , POLD1(5424) , POLG(5428)

 

安全信息

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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