<br /> Empirical Formula (Hill Notation): C66H68F2N4O10 · Ca · 3H2O CAS号: 344423-98-9 分子量: 1209.39">
阿托伐他汀钙盐三水合物是β-羟基β-甲基戊二酰辅酶a(HMG-CoA)还原酶的特异性抑制剂。HMG-CoA还原酶是催化HMG-CoA转化为甲羟戊酸的酶,这是胆固醇生物合成的早期步骤。阿托伐他汀用于治疗高胆固醇血症。
100
≥98% (HPLC)
powder
[α]/D -9.0 to -5.0°, c = 0.5 in DMSO
protect from light
white to beige
DMSO: 2 mg/mL, clear
room temp
O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Ca+2].[3.0H2O]
Danger
Carc. 2 - Repr. 1B
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK 3