辣椒碱 [辣椒素]，Capsaicin；natural, 63.7% (HPLC)

Capsaicin (Zostrix), an alkaloid extract is obtained from hot chili peppers.[1][2] It is accessible in the form of cream and lotion.[1] Capsaicin is a hydrophobic, instable and pungent white crystalline powder, that has no smell and color. It is produced by mixing a branched-chain fatty acid to vanillylamine in the chili pepper.[3]

 

Capsaicin has been used in the development of the isolation methods.[4] It has also been used in the development of enzyme based electrochemical biosensor for the determination of capsaicin using a novel signal amplification strategy.[5]

 

原型香草受体激动剂。 神经毒素；激活产生无髓C纤维的感觉神经元，其中许多含有P物质。 局部使用可使感觉神经末梢脱敏，从而产生反常的抗伤害感受作用；全身给药可对辣椒素敏感的细胞产生神经毒性，尤其是在新生动物中。辣椒的活性成分。

Capsaicin is used as an important component of oleoresin capsicum or pepper spray.[6] It plays a beneficial role in obesity, cardiovascular and gastrointestinal conditions, several cancers, neurogenic bladder and dermatologic conditions.[3] It is used in the production of spices, chilli sauces and pain-inducing defensive pepper sprays. Capsaicin is also used to manufacture creams to treat diabetic neuropathy, cluster headache, psoriasis, rheumatoid arthritis and reflex sympathetic dystrophy.[2] It is considered as an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1).[3]